List of publications from the PROFORMA Project

  1. Fimbo, A. M., Mnkugwe, R. H., Mlugu, E. M., Kunambi, P. P., Malishee, A., Minzi, O. M. S., Kamuhabwa, A. A. R., & Aklillu, E. Efficacy of ivermectin and albendazole combination in suppressing transmission of lymphatic filariasis following mass administration in Tanzania: a prospective cohort study. Infect Dis Poverty,2024;  13, 44. https://doi.org/10.1186/s40249-024-01214-3.
  2. van Puijenbroek, E., Barry, A., Khaemba, C., Ntirenganya, L., Gebreyesus, T. D., Fimbo, A., Minzi, O., Makonnen, E., Oluka, M., Guantai, A., & Aklillu, E. Short-Term Training, a Useful Approach for Sustainable Pharmacovigilance Knowledge Development in Tanzania, Kenya, Ethiopia and Rwanda. Drug Saf,2024; https://doi.org/10.1007/s40264-024-01469-7.
  3. Gebreyesus, T.D.; Makonnen, E.; Telele, N.F.; Barry, A.; Mnkugwe, R.H.; Gerba, H.; Dahl, M.L.; Aklillu, E. CYP2C19 and CYP2J2 genotypes predict praziquantel plasma exposure among Ethiopian school-aged children. Sci Rep; 2024, 14, 11730. https://doi.org/10.1038/s41598-024-62669-w.
  4. Gebreyesus, T.D.; Makonnen, E.; Tadele, T.; Mekete, K.; Gashaw, H.; Gerba, H.; Aklillu, E. Reduced efficacy of single-dose albendazole against Ascaris lumbricoides, and Trichuris trichiura, and high reinfection rate after cure among school children in southern Ethiopia: a prospective cohort study. Infect Dis Poverty; 2024, 13, 8. https://doi.org/10.1186/s40249-024-01176-6.
  5. Tadele, T.; Astatkie, A.; Tadesse, B.T.; Makonnen, E.; Aklillu, E.; Abay, S.M. Efficacy and safety of praziquantel treatment against Schistosoma mansoni infection among pre-school age children in southern Ethiopia. Trop Med Health; 2023, 51, 72. https://doi.org/10.1186/s41182-023-00562-4.
  6. Tadele, T.; Astatkie, A.; Abay, S.M.; Tadesse, B.T.; Makonnen, E.; Aklillu, E. Prevalence and Determinants of Schistosoma mansoni Infection among Pre-School Age Children in Southern Ethiopia. Pathogens; 2023, 12, https://doi.org/10.3390/pathogens12070858.
  7. Khaemba, C.; Barry, A.; Omondi, W.P.; Kirui, E.; Oluka, M.; Parthasarathi, G.; Njenga, S.M.; Guantai, A.; Aklillu, E. Comparative Safety Surveillance of Triple (IDA) Versus Dual Therapy (DA) in Mass Drug Administration for Elimination of Lymphatic Filariasis in Kenya: A Cohort Event Monitoring Study. Drug Saf; 2023, 46, 961-974. https://doi.org/10.1007/s40264-023-01338-9.
  8. Kabatende, J.; Ntirenganya, L.; Mugisha, M.; Barry, A.; Ruberanziza, E.; Bienvenu, E.; Bergman, U.; Aklillu, E. Efficacy of Single-Dose Praziquantel for the Treatment of Schistosoma mansoni Infections among School Children in Rwanda. Pathogens; 2023, 12, https://doi.org/10.3390/pathogens12091170.
  9. Kabatende, J.; Barry, A.; Mugisha, M.; Ntirenganya, L.; Bergman, U.; Bienvenu, E.; Aklillu, E. Efficacy of Single-Dose Albendazole for the Treatment of Soil-Transmitted Helminthic Infections among School Children in Rwanda-A Prospective Cohort Study. Pharmaceuticals (Basel); 2023, 16, https://doi.org/10.3390/ph16020139.
  10. Gebreyesus, T.D.; Makonnen, E.; Tadele, T.; Mekete, K.; Gashaw, H.; Gerba, H.; Aklillu, E. Efficacy and safety of praziquantel preventive chemotherapy in Schistosoma mansoni infected school children in Southern Ethiopia: A prospective cohort study. Front Pharmacol; 2023, 14, 968106. https://doi.org/10.3389/fphar.2023.968106.
  11. Fimbo, A.M.; Mlugu, E.M.; Kitabi, E.N.; Kulwa, G.S.; Iwodyah, M.A.; Mnkugwe, R.H.; Kunambi, P.P.; Malishee, A.; Kamuhabwa, A.A.R.; Minzi, O.M.; Aklillu, E. Population pharmacokinetics of ivermectin after mass drug administration in lymphatic filariasis endemic communities of Tanzania. CPT Pharmacometrics Syst Pharmacol; 2023, 12, 1884-1896. https://doi.org/10.1002/psp4.13038.
  12. Barry, A.; Kabatende, J.; Telele, N.F.; Mnkugwe, R.H.; Mugisha, M.; Ntirenganya, L.; Bienvenu, E.; Aklillu, E. Effect of pharmacogenetic variations on praziquantel plasma concentration and safety outcomes among school children in Rwanda. Sci Rep; 2023, 13, 1446. https://doi.org/10.1038/s41598-023-28641-w.
  13. Kabatende, J.; Barry, A.; Mugisha, M.; Ntirenganya, L.; Bergman, U.; Bienvenu, E.; Aklillu, E. Safety of Praziquantel and Albendazole Coadministration for the Control and Elimination of Schistosomiasis and Soil-Transmitted Helminths Among Children in Rwanda: An Active Surveillance Study. Drug Saf; 2022, 45, 909-922. https://doi.org/10.1007/s40264-022-01201-3.
  14. Gebreyesus, T.D.; Makonnen, E.; Tadele, T.; Gashaw, H.; Degefe, W.; Gerba, H.; Tadesse, B.T.; Gurumurthy, P.; Aklillu, E. Safety Surveillance of Mass Praziquantel and Albendazole Co-Administration in School Children from Southern Ethiopia: An Active Cohort Event Monitoring. J Clin Med; 2022, 11, https://doi.org/10.3390/jcm11216300.
  15. Fimbo, A.M.; Minzi, O.M.; Mmbando, B.P.; Gurumurthy, P.; Kamuhabwa, A.A.R.; Aklillu, E. Safety and Tolerability of Ivermectin and Albendazole Mass Drug Administration in Lymphatic Filariasis Endemic Communities of Tanzania: A Cohort Event Monitoring Study. Pharmaceuticals (Basel); 2022, 15, https://doi.org/10.3390/ph15050594.
  16. Mnkugwe, R.H.; Ngaimisi Kitabi, E.; Kinung’hi, S.; Kamuhabwa, A.A.R.; Minzi, O.M.; Aklillu, E. Optimal single sampling time-point for monitoring of praziquantel exposure in children. Sci Rep; 2021, 11, 17955. https://doi.org/10.1038/s41598-021-97409-x.
  17. Mnkugwe, R.H.; Minzi, O.; Kinung’hi, S.; Kamuhabwa, A.; Aklillu, E. Effect of Pharmacogenetics Variations on Praziquantel Plasma Concentrations and Schistosomiasis Treatment Outcomes Among Infected School-Aged Children in Tanzania. Front Pharmacol; 2021, 12, 712084. https://doi.org/10.3389/fphar.2021.712084.
  18. Minzi, O.M.; Mnkugwe, R.H.; Ngaimisi, E.; Kinung’hi, S.; Hansson, A.; Pohanka, A.; Kamuhabwa, A.; Aklillu, E. Effect of Dihydroartemisinin-Piperaquine on the Pharmacokinetics of Praziquantel for Treatment of Schistosoma mansoni Infection. Pharmaceuticals (Basel); 2021, 14, https://doi.org/10.3390/ph14050400.
  19. Khaemba, C.; Barry, A.; Omondi, W.P.; Bota, K.; Matendechero, S.; Wandera, C.; Siyoi, F.; Kirui, E.; Oluka, M.; Nambwa, P.; Gurumurthy, P.; Njenga, S.M.; Guantai, A.; Aklillu, E. Safety and Tolerability of Mass Diethylcarbamazine and Albendazole Administration for the Elimination of Lymphatic Filariasis in Kenya: An Active Surveillance Study. Pharmaceuticals (Basel); 2021, 14, https://doi.org/10.3390/ph14030264.
  20. Barry, A.; Olsson, S.; Khaemba, C.; Kabatende, J.; Dires, T.; Fimbo, A.; Minzi, O.; Bienvenu, E.; Makonnen, E.; Kamuhabwa, A.; Oluka, M.; Guantai, A.; van Puijenbroek, E.; Bergman, U.; Nkayamba, A.; Mugisha, M.; Gurumurthy, P.; Aklillu, E. Comparative Assessment of the Pharmacovigilance Systems within the Neglected Tropical Diseases Programs in East Africa-Ethiopia, Kenya, Rwanda, and Tanzania. Int J Environ Res Public Health; 2021, 18, https://doi.org/10.3390/ijerph18041941.
  21. Mnkugwe, R.H.; Minzi, O.S.; Kinung’hi, S.M.; Kamuhabwa, A.A.; Aklillu, E. Prevalence and correlates of intestinal schistosomiasis infection among school-aged children in North-Western Tanzania. PLoS One; 2020, 15, e0228770. https://doi.org/10.1371/journal.pone.0228770.
  22. Mnkugwe, R.H.; Minzi, O.; Kinung’hi, S.; Kamuhabwa, A.; Aklillu, E. Efficacy and safety of praziquantel and dihydroartemisinin piperaquine combination for treatment and control of intestinal schistosomiasis: A randomized, non-inferiority clinical trial. PLoS Negl Trop Dis; 2020, 14, e0008619. https://doi.org/10.1371/journal.pntd.0008619.
  23. Kabatende, J.; Mugisha, M.; Ntirenganya, L.; Barry, A.; Ruberanziza, E.; Mbonigaba, J.B.; Bergman, U.; Bienvenu, E.; Aklillu, E. Prevalence, Intensity, and Correlates of Soil-Transmitted Helminth Infections among School Children after a Decade of Preventive Chemotherapy in Western Rwanda. Pathogens; 2020, 9, https://doi.org/10.3390/pathogens9121076.
  24. Gebreyesus, T.D.; Tadele, T.; Mekete, K.; Barry, A.; Gashaw, H.; Degefe, W.; Tadesse, B.T.; Gerba, H.; Gurumurthy, P.; Makonnen, E.; Aklillu, E. Prevalence, Intensity, and Correlates of Schistosomiasis and Soil-Transmitted Helminth Infections after Five Rounds of Preventive Chemotherapy among School Children in Southern Ethiopia. Pathogens; 2020, 9, https://doi.org/10.3390/pathogens9110920.
  25. Fimbo, A.M.; Minzi, O.M.S.; Mmbando, B.P.; Barry, A.; Nkayamba, A.F.; Mwamwitwa, K.W.; Malishee, A.; Seth, M.D.; Makunde, W.H.; Gurumurthy, P.; Lusingu, J.P.A.; Kamuhabwa, A.A.R.; Aklillu, E. Prevalence and Correlates of Lymphatic Filariasis Infection and Its Morbidity Following Mass Ivermectin and Albendazole Administration in Mkinga District, North-Eastern Tanzania. J Clin Med; 2020, 9, https://doi.org/10.3390/jcm9051550.
  26. Barry, A.; Olsson, S.; Minzi, O.; Bienvenu, E.; Makonnen, E.; Kamuhabwa, A.; Oluka, M.; Guantai, A.; Bergman, U.; van Puijenbroek, E.; Gurumurthy, P.; Aklillu, E. Comparative Assessment of the National Pharmacovigilance Systems in East Africa: Ethiopia, Kenya, Rwanda and Tanzania. Drug Saf; 2020, 43, 339-350. https://doi.org/10.1007/s40264-019-00898-z.
  27. Mnkugwe, R.H.; Minzi, O.S.; Kinung’hi, S.M.; Kamuhabwa, A.A.; Aklillu, E. Efficacy and Safety of Praziquantel for Treatment of Schistosoma mansoni Infection among School Children in Tanzania. Pathogens; 2019, 9, https://doi.org/10.3390/pathogens9010028.

Updated by:

kiwp 2024-10-23